Cargando…

The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa

BACKGROUND: Most animals employ telomerase, which consists of a catalytic subunit known as the telomerase reverse transcriptase (TERT) and an RNA template, to maintain telomere ends. Given the importance of TERT and telomere biology in core metazoan life history traits, like ageing and the control o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Alvina G., Pouchkina-Stantcheva, Natalia, Di Donfrancesco, Alessia, Kildisiute, Gerda, Sahu, Sounak, Aboobaker, A. Aziz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405514/ https://www.ncbi.nlm.nih.gov/pubmed/28441946 http://dx.doi.org/10.1186/s12862-017-0949-4

Ejemplares similares

Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells
por: Dattani, Anish, et al.
Publicado: (2018)

The abrogation of condensin function provides independent evidence for defining the self-renewing population of pluripotent stem cells
por: Lai, Alvina G., et al.
Publicado: (2018)

Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa
por: Oliver, Peter L., et al.
Publicado: (2009)

Comparative genomic analysis of innate immunity reveals novel and conserved components in crustacean food crop species
por: Lai, Alvina G., et al.
Publicado: (2017)

Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints
por: Irimia, Manuel, et al.
Publicado: (2012)

Hemotin, a Regulator of Phagocytosis Encoded by a Small ORF and Conserved across Metazoans
por: Pueyo, José I., et al.
Publicado: (2016)

Profusion of G-quadruplexes on both subunits of metazoan ribosomes
por: Mestre-Fos, Santi, et al.
Publicado: (2019)

Measuring genome conservation across taxa: divided strains and united kingdoms
por: Kunin, Victor, et al.
Publicado: (2005)

Mitochondria, Telomeres and Telomerase Subunits
por: Zheng, Qian, et al.
Publicado: (2019)

Conservation of Complete Trimethylation of Lysine-43 in the Rotor Ring of c-Subunits of Metazoan Adenosine Triphosphate (ATP) Synthases
por: Walpole, Thomas B., et al.
Publicado: (2015)

Deeply conserved synteny and the evolution of metazoan chromosomes
por: Simakov, Oleg, et al.
Publicado: (2022)

Conservation of epigenetic regulation by the MLL3/4 tumour suppressor in planarian pluripotent stem cells
por: Mihaylova, Yuliana, et al.
Publicado: (2018)

Transposon-derived transcription factors across metazoans
por: Mukherjee, Krishanu, et al.
Publicado: (2023)

Absence of telomerase activity and telomerase catalytic subunit mRNA in melanocyte cultures
por: Dhaene, K, et al.
Publicado: (2000)

Ongoing repair of migration-coupled DNA damage allows planarian adult stem cells to reach wound sites
por: Sahu, Sounak, et al.
Publicado: (2021)

The genome of the crustacean Parhyale hawaiensis, a model for animal development, regeneration, immunity and lignocellulose digestion
por: Kao, Damian, et al.
Publicado: (2016)

The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae
por: Hass, Evan P, et al.
Publicado: (2015)

Molecular mechanisms of sperm motility are conserved in an early-branching metazoan
por: Speer, Kelsey F., et al.
Publicado: (2021)

Substitution Patterns Are GC-Biased in Divergent Sequences across the Metazoans
por: Capra, John A., et al.
Publicado: (2011)

The origin and distribution of the main oxygen sensing mechanism across metazoans
por: Song, Bing, et al.
Publicado: (2022)

trt-1 Is the Caenorhabditis elegans Catalytic Subunit of Telomerase
por: Meier, Bettina, et al.
Publicado: (2006)

Immortalization of Human Keratinocytes Using the Catalytic Subunit of Telomerase
por: Beilin, A. K., et al.
Publicado: (2021)

MVB-12, a Fourth Subunit of Metazoan ESCRT-I, Functions in Receptor Downregulation
por: Audhya, Anjon, et al.
Publicado: (2007)

Temperature sensitivities of metazoan and pre-metazoan Src kinases
por: Miller, W. Todd
Publicado: (2020)

Spiders fluoresce variably across many taxa
por: Andrews, Kindra, et al.
Publicado: (2007)

The human telomerase catalytic subunit and viral telomerase RNA reconstitute a functional telomerase complex in a cell-free system, but not in human cells
por: Trapp-Fragnet, Laetitia, et al.
Publicado: (2012)

Narrowly distributed taxa are disproportionately informative for conservation planning
por: Akasaka, Munemitsu, et al.
Publicado: (2022)

Data-Driven Inference Reveals Distinct and Conserved Dynamic Pathways of Tool Use Emergence across Animal Taxa
por: Johnston, Iain G., et al.
Publicado: (2020)

An Evolutionary Landscape of A-to-I RNA Editome across Metazoan Species
por: Hung, Li-Yuan, et al.
Publicado: (2017)

Glass confers rhabdomeric photoreceptor identity in Drosophila, but not across all metazoans
por: Bernardo-Garcia, F. Javier, et al.
Publicado: (2019)

Probing the origins of metazoan formin diversity: Evidence for evolutionary relationships between metazoan and non-metazoan formin subtypes
por: Pruyne, David
Publicado: (2017)

P. berghei Telomerase Subunit TERT is Essential for Parasite Survival
por: Religa, Agnieszka A., et al.
Publicado: (2014)

The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres
por: Frank, Amanda K., et al.
Publicado: (2015)

Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms
por: Lewis, Kayla A., et al.
Publicado: (2016)

Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer Therapy
por: Eckburg, Adam, et al.
Publicado: (2020)

Cryo‐EM structure of metazoan TRAPPIII, the multi‐subunit complex that activates the GTPase Rab1
por: Galindo, Antonio, et al.
Publicado: (2021)

MetaCOXI: an integrated collection of metazoan mitochondrial cytochrome oxidase subunit-I DNA sequences
por: Balech, Bachir, et al.
Publicado: (2022)

Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype
por: Rohn, Jennifer L., et al.
Publicado: (2011)

Constraints on genes shape long-term conservation of macro-synteny in metazoan genomes
por: Lv, Jie, et al.
Publicado: (2011)

The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity
por: de Mendoza, Alex, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k874ng0vlkvprgilb01ucrd5gg