Induction of Pluripotent Stem Cells from a Manifesting Carrier of Duchenne Muscular Dystrophy and Characterization of Their X-Inactivation Status

Three to eight percent of female carriers of Duchenne muscular dystrophy (DMD) develop dystrophic symptoms ranging from mild muscle weakness to a rapidly progressive DMD-like muscular dystrophy due to skewed inactivation of X chromosomes during early development. Here, we generated human induced plu...

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Detalles Bibliográficos
Autores principales: Miyagoe-Suzuki, Yuko, Nishiyama, Takashi, Nakamura, Miho, Narita, Asako, Takemura, Fusako, Masuda, Satoru, Minami, Narihiro, Murayama, Kumiko, Komaki, Hirofumi, Goto, Yu-ichi, Takeda, Shin'ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405591/
https://www.ncbi.nlm.nih.gov/pubmed/28491099
http://dx.doi.org/10.1155/2017/7906843

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