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Antidepressant-induced Dopamine Receptor Dysregulation: A Valid Animal Model of Manic-Depressive Illness

Background: Mania seems to be associated with an increased dopamine (DA) transmission. Antidepressant treatments can induce mania in humans and potentiated DA transmission in animals, by sensitizing DA D2 receptors in the mesolimbic system. We have suggested that the sensitization of D2 receptors ma...

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Detalles Bibliográficos
Autores principales: Demontis, Francesca, Serra, Francesca, Serra, Gino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405612/
https://www.ncbi.nlm.nih.gov/pubmed/28503114
http://dx.doi.org/10.2174/1570159X14666160715165648