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Hypomethylating agents synergize with irinotecan to improve response to chemotherapy in colorectal cancer cells
Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. In the metastatic setting, the majority of patients respond to initial therapies but eventually develop resistance and progress. In this study, we test the hypothesis that priming with epigenetic therapy sensit...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405959/ https://www.ncbi.nlm.nih.gov/pubmed/28445481 http://dx.doi.org/10.1371/journal.pone.0176139 |