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Hypomethylating agents synergize with irinotecan to improve response to chemotherapy in colorectal cancer cells

Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. In the metastatic setting, the majority of patients respond to initial therapies but eventually develop resistance and progress. In this study, we test the hypothesis that priming with epigenetic therapy sensit...

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Detalles Bibliográficos
Autores principales:	Sharma, Anup, Vatapalli, Rajita, Abdelfatah, Eihab, Wyatt McMahon, K., Kerner, Zachary, A. Guzzetta, Angela, Singh, Jasvinder, Zahnow, Cynthia, B. Baylin, Stephen, Yerram, Sashidhar, Hu, Yue, Azad, Nilofer, Ahuja, Nita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405959/ https://www.ncbi.nlm.nih.gov/pubmed/28445481 http://dx.doi.org/10.1371/journal.pone.0176139

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