Cargando…
Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease
Infection of various cells with Theiler’s murine encephalomyelitis virus (TMEV) activates the TLR- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways, resulting in the production of IL-1β via the activation of caspase-1 upon assembly of the node-like receptor protein 3 (NLRP3)...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406002/ https://www.ncbi.nlm.nih.gov/pubmed/28445497 http://dx.doi.org/10.1371/journal.pone.0176406 |