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Prostaglandin E2 produced following infection with Theiler's virus promotes the pathogenesis of demyelinating disease

Infection of various cells with Theiler’s murine encephalomyelitis virus (TMEV) activates the TLR- and melanoma differentiation-associated gene 5 (MDA5)-dependent pathways, resulting in the production of IL-1β via the activation of caspase-1 upon assembly of the node-like receptor protein 3 (NLRP3)...

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Detalles Bibliográficos
Autores principales:	Kim, Seung Jae, Jin, Young-Hee, Kim, Byung S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406002/ https://www.ncbi.nlm.nih.gov/pubmed/28445497 http://dx.doi.org/10.1371/journal.pone.0176406

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