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RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection
The type I interferon pathway plays a critical role in both host defense and tolerance against viral infection and thus requires refined regulatory mechanisms. RIPK3-mediated necroptosis has been shown to be involved in anti-viral immunity. However, the exact role of RIPK3 in immunity to Influenza A...
Autores principales: | Downey, Jeffrey, Pernet, Erwan, Coulombe, François, Allard, Benoit, Meunier, Isabelle, Jaworska, Joanna, Qureshi, Salman, Vinh, Donald C., Martin, James G., Joubert, Philippe, Divangahi, Maziar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406035/ https://www.ncbi.nlm.nih.gov/pubmed/28410401 http://dx.doi.org/10.1371/journal.ppat.1006326 |
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