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Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study
Functional dyspepsia (FD) is a constellation of epigastric symptoms originating in the gastroduodenal region without organic and metabolic cause. However, similar confounding symptoms can also appear in patients with gallbladder (GB) dyskinesia. Therefore, symptoms of GB dyskinesia may be mistaken f...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406103/ https://www.ncbi.nlm.nih.gov/pubmed/28422887 http://dx.doi.org/10.1097/MD.0000000000006702 |
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author | Jung, Sung Won Joo, Min Sun Choi, Hyun Chang Jang, Sung Ill Woo, Young Sik Kim, Jin Bae Park, Sang Hoon Lee, Myung Seok |
author_facet | Jung, Sung Won Joo, Min Sun Choi, Hyun Chang Jang, Sung Ill Woo, Young Sik Kim, Jin Bae Park, Sang Hoon Lee, Myung Seok |
author_sort | Jung, Sung Won |
collection | PubMed |
description | Functional dyspepsia (FD) is a constellation of epigastric symptoms originating in the gastroduodenal region without organic and metabolic cause. However, similar confounding symptoms can also appear in patients with gallbladder (GB) dyskinesia. Therefore, symptoms of GB dyskinesia may be mistaken for FD. We aimed to identify GB dyskinesia as a cause of FD symptoms compatible with the Rome IV criteria and the need for an evaluation of GB function in patients with FD symptoms. We investigated information of patients with FD symptoms who underwent a quantitative (99)Tc(m)-diisoproyl iminodiacetic acid cholescintigraphy (DISIDA scan) through electronic medical records, and GB dyskinesia was judged to be the cause of the FD symptoms if the symptoms disappeared as GB function normalized on the follow-up DISIA scan in patient with decreased GB function on the initial DISIDA scan. A total of 275 patients underwent a DISIDA scan. Eighteen patients of them had FD symptoms compatible with the Rome IV criteria. Three were lost after undergoing a DISIDA scan. Eight had normal GB function, and the other 7 had decreased GB function on the initial DISIDA scan. In 4 of the 7 patients with GB dyskinesia, FD symptoms disappeared as GB function normalized. As a result, GB dyskinesia was the cause of the symptoms in 4 of 18 patients with FD symptoms compatible with the Rome IV criteria. It is necessary to evaluate GB function in patients with refractory FD symptoms because the symptoms can be caused by GB dyskinesia. |
format | Online Article Text |
id | pubmed-5406103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-54061032017-04-28 Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study Jung, Sung Won Joo, Min Sun Choi, Hyun Chang Jang, Sung Ill Woo, Young Sik Kim, Jin Bae Park, Sang Hoon Lee, Myung Seok Medicine (Baltimore) 4500 Functional dyspepsia (FD) is a constellation of epigastric symptoms originating in the gastroduodenal region without organic and metabolic cause. However, similar confounding symptoms can also appear in patients with gallbladder (GB) dyskinesia. Therefore, symptoms of GB dyskinesia may be mistaken for FD. We aimed to identify GB dyskinesia as a cause of FD symptoms compatible with the Rome IV criteria and the need for an evaluation of GB function in patients with FD symptoms. We investigated information of patients with FD symptoms who underwent a quantitative (99)Tc(m)-diisoproyl iminodiacetic acid cholescintigraphy (DISIDA scan) through electronic medical records, and GB dyskinesia was judged to be the cause of the FD symptoms if the symptoms disappeared as GB function normalized on the follow-up DISIA scan in patient with decreased GB function on the initial DISIDA scan. A total of 275 patients underwent a DISIDA scan. Eighteen patients of them had FD symptoms compatible with the Rome IV criteria. Three were lost after undergoing a DISIDA scan. Eight had normal GB function, and the other 7 had decreased GB function on the initial DISIDA scan. In 4 of the 7 patients with GB dyskinesia, FD symptoms disappeared as GB function normalized. As a result, GB dyskinesia was the cause of the symptoms in 4 of 18 patients with FD symptoms compatible with the Rome IV criteria. It is necessary to evaluate GB function in patients with refractory FD symptoms because the symptoms can be caused by GB dyskinesia. Wolters Kluwer Health 2017-04-21 /pmc/articles/PMC5406103/ /pubmed/28422887 http://dx.doi.org/10.1097/MD.0000000000006702 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | 4500 Jung, Sung Won Joo, Min Sun Choi, Hyun Chang Jang, Sung Ill Woo, Young Sik Kim, Jin Bae Park, Sang Hoon Lee, Myung Seok Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study |
title | Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study |
title_full | Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study |
title_fullStr | Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study |
title_full_unstemmed | Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study |
title_short | Epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: Retrospective observational study |
title_sort | epigastric symptoms of gallbladder dyskinesia mistaken for functional dyspepsia: retrospective observational study |
topic | 4500 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406103/ https://www.ncbi.nlm.nih.gov/pubmed/28422887 http://dx.doi.org/10.1097/MD.0000000000006702 |
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