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Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription
OBJECTIVES: To describe a case of neuroleptic malignant syndrome following antipsychotic treatment of catatonia, highlighting the potentially serious complications of this rare adverse drug reaction. METHODS: We present a case report of a patient who developed this syndrome with various sequelae. RE...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406192/ https://www.ncbi.nlm.nih.gov/pubmed/28491312 http://dx.doi.org/10.1177/2050313X17695999 |
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author | Reilly, Thomas J Cross, Sean Taylor, David M Haslam, Richard Tomlin, Sophie C Gaastra, Benjamin |
author_facet | Reilly, Thomas J Cross, Sean Taylor, David M Haslam, Richard Tomlin, Sophie C Gaastra, Benjamin |
author_sort | Reilly, Thomas J |
collection | PubMed |
description | OBJECTIVES: To describe a case of neuroleptic malignant syndrome following antipsychotic treatment of catatonia, highlighting the potentially serious complications of this rare adverse drug reaction. METHODS: We present a case report of a patient who developed this syndrome with various sequelae. RESULTS: The patient developed neuroleptic after being treated with lorazepam and olanzapine for catatonia. He subsequently developed the complications of rhabdomyolysis, acute kidney injury, pulmonary embolism, urinary retention and ileus. He received high-dose lorazepam, anticoagulation and intravenous fluids. Antipsychotic medication in the form of haloperidol was reinstated with no adverse effect, and he went on to make a full recovery. CONCLUSIONS: This case illustrates the potential life-threatening complications of neuroleptic malignant syndrome and the need for a low index of clinical suspicion. It also highlights the lack of evidence for treatment of catatonia, including the use of antipsychotics. |
format | Online Article Text |
id | pubmed-5406192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-54061922017-05-10 Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription Reilly, Thomas J Cross, Sean Taylor, David M Haslam, Richard Tomlin, Sophie C Gaastra, Benjamin SAGE Open Med Case Rep Case Report OBJECTIVES: To describe a case of neuroleptic malignant syndrome following antipsychotic treatment of catatonia, highlighting the potentially serious complications of this rare adverse drug reaction. METHODS: We present a case report of a patient who developed this syndrome with various sequelae. RESULTS: The patient developed neuroleptic after being treated with lorazepam and olanzapine for catatonia. He subsequently developed the complications of rhabdomyolysis, acute kidney injury, pulmonary embolism, urinary retention and ileus. He received high-dose lorazepam, anticoagulation and intravenous fluids. Antipsychotic medication in the form of haloperidol was reinstated with no adverse effect, and he went on to make a full recovery. CONCLUSIONS: This case illustrates the potential life-threatening complications of neuroleptic malignant syndrome and the need for a low index of clinical suspicion. It also highlights the lack of evidence for treatment of catatonia, including the use of antipsychotics. SAGE Publications 2017-03-31 /pmc/articles/PMC5406192/ /pubmed/28491312 http://dx.doi.org/10.1177/2050313X17695999 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution 3.0 License (http://www.creativecommons.org/licenses/by/3.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Reilly, Thomas J Cross, Sean Taylor, David M Haslam, Richard Tomlin, Sophie C Gaastra, Benjamin Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription |
title | Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription |
title_full | Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription |
title_fullStr | Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription |
title_full_unstemmed | Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription |
title_short | Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription |
title_sort | neuroleptic malignant syndrome following catatonia: vigilance is the price of antipsychotic prescription |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406192/ https://www.ncbi.nlm.nih.gov/pubmed/28491312 http://dx.doi.org/10.1177/2050313X17695999 |
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