LRP1 Modulates APP Intraneuronal Transport and Processing in Its Monomeric and Dimeric State

The low-density lipoprotein receptor-related protein 1, LRP1, interacts with APP and affects its processing. This is assumed to be mostly caused by the impact of LRP1 on APP endocytosis. More recently, also an interaction of APP and LRP1 early in the secretory pathway was reported whereat retention...

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Detalles Bibliográficos
Autores principales: Herr, Uta-Mareike, Strecker, Paul, Storck, Steffen E., Thomas, Carolin, Rabiej, Verena, Junker, Anne, Schilling, Sandra, Schmidt, Nadine, Dowds, C. Marie, Eggert, Simone, Pietrzik, Claus U., Kins, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406469/
https://www.ncbi.nlm.nih.gov/pubmed/28496400
http://dx.doi.org/10.3389/fnmol.2017.00118

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