Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer

To identify potential therapeutic targets for lung cancer, we performed semi‐genome‐wide shRNA screening combined with the utilization of genome‐wide expression and copy number data. shRNA screening targeting 5043 genes in NCI‐H460 identified 51 genes as candidates. Pathway analysis revealed that th...

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Detalles Bibliográficos
Autores principales: Kakumu, Tomohiko, Sato, Mitsuo, Goto, Daiki, Kato, Toshio, Yogo, Naoyuki, Hase, Tetsunari, Morise, Masahiro, Fukui, Takayuki, Yokoi, Kohei, Sekido, Yoshitaka, Girard, Luc, Minna, John D., Byers, Lauren A., Heymach, John V., Coombes, Kevin R., Kondo, Masashi, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406588/
https://www.ncbi.nlm.nih.gov/pubmed/28165654
http://dx.doi.org/10.1111/cas.13185

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