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Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin‐containing protein inhibitor

Xanthohumol (XN), a simple prenylated chalcone, can be isolated from hops and has the potential to be a cancer chemopreventive agent against several human tumor cell lines. We previously identified valosin‐containing protein (VCP) as a target of XN; VCP can also play crucial roles in cancer progress...

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Detalles Bibliográficos
Autores principales: Shikata, Yuki, Yoshimaru, Tetsuro, Komatsu, Masato, Katoh, Hiroto, Sato, Reiko, Kanagaki, Shuhei, Okazaki, Yasumasa, Toyokuni, Shinya, Tashiro, Etsu, Ishikawa, Shumpei, Katagiri, Toyomasa, Imoto, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406609/
https://www.ncbi.nlm.nih.gov/pubmed/28122154
http://dx.doi.org/10.1111/cas.13175