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Protein kinase A inhibition facilitates the antitumor activity of xanthohumol, a valosin‐containing protein inhibitor
Xanthohumol (XN), a simple prenylated chalcone, can be isolated from hops and has the potential to be a cancer chemopreventive agent against several human tumor cell lines. We previously identified valosin‐containing protein (VCP) as a target of XN; VCP can also play crucial roles in cancer progress...
Autores principales: | Shikata, Yuki, Yoshimaru, Tetsuro, Komatsu, Masato, Katoh, Hiroto, Sato, Reiko, Kanagaki, Shuhei, Okazaki, Yasumasa, Toyokuni, Shinya, Tashiro, Etsu, Ishikawa, Shumpei, Katagiri, Toyomasa, Imoto, Masaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406609/ https://www.ncbi.nlm.nih.gov/pubmed/28122154 http://dx.doi.org/10.1111/cas.13175 |
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