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Search for Modified DNA Sites with the Human Methyl-CpG-Binding Enzyme MBD4

The MBD4 enzyme initiates the process of DNA demethylation by the excision of modified DNA bases, resulting in the formation of apurinic/apyrimidinic sites. MBD4 contains a methyl-CpG-binding domain which provides the localization of the enzyme at the CpG sites, and a DNA glycosylase domain that is...

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Detalles Bibliográficos
Autores principales:	Yakovlev, D. A., Kuznetsova, A. A., Fedorova, O. S., Kuznetsov, N. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	A.I. Gordeyev 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406665/ https://www.ncbi.nlm.nih.gov/pubmed/28461979

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