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Antiretroviral Activity Of a Novel Pyrimidyl-Di(Diazaspiroalkane) Derivative

A novel compound, 3,3’-(5-nitropyrimidine-4,6-diyl)bis-3,12-diaza-6,9-diazoniadispiro[5.2.5.2]hexadecane tetrachloride dihydrochloride, was synthesized. The compound was found to inhibit the replication of various viral families by blocking specific heparan sulfate receptors on the host cell’s surfa...

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Detalles Bibliográficos
Autores principales: Novoselova, E.A., Riabova, O.B., Leneva, I.A., Nesterenko, V.G., Bolgarin, R.N., Makarov, V.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406667/
https://www.ncbi.nlm.nih.gov/pubmed/28461981