Cargando…

Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment

The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells. Fibroblasts are the predominant constituent of the tumor stroma an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Owusu, Benjamin Yaw, Galemmo, Robert, Janetka, James, Klampfer, Lidija
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406710/ https://www.ncbi.nlm.nih.gov/pubmed/28420162 http://dx.doi.org/10.3390/cancers9040035

Ejemplares similares

Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation
por: Owusu, Benjamin Y., et al.
Publicado: (2017)

Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling
por: Owusu, Benjamin Y., et al.
Publicado: (2016)

Prognostic and Predictive Significance of Stromal Fibroblasts and Macrophages in Colon Cancer
por: Owusu, Benjamin Y., et al.
Publicado: (2015)

Key roles of necroptotic factors in promoting tumor growth
por: Liu, Xinjian, et al.
Publicado: (2016)

The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment
por: Fu, Haiyan, et al.
Publicado: (2021)

The Role of STAT1 for Crosstalk between Fibroblasts and Colon Cancer Cells
por: Kaler, Pawan, et al.
Publicado: (2014)

Tumor Associated Macrophages Protect Colon Cancer Cells from TRAIL-Induced Apoptosis through IL-1β- Dependent Stabilization of Snail in Tumor Cells
por: Kaler, Pawan, et al.
Publicado: (2010)

Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine
por: Kawaguchi, Makiko, et al.
Publicado: (2019)

Tumor-associated stromal cells as key contributors to the tumor microenvironment
por: Bussard, Karen M., et al.
Publicado: (2016)

Multifaceted Interplay between Hormones, Growth Factors and Hypoxia in the Tumor Microenvironment
por: Lappano, Rosamaria, et al.
Publicado: (2022)

A review on hepatocyte nuclear factor-1beta and tumor
por: Yu, Dan-Dan, et al.
Publicado: (2015)

Differences of macrophages in the tumor microenvironment as an underlying key factor in glioma patients
por: Wang, Yangyang, et al.
Publicado: (2022)

Growth hormone in the tumor microenvironment
por: Chesnokova, Vera, et al.
Publicado: (2019)

Transforming growth factor-β signaling: from tumor microenvironment to anticancer therapy
por: Chan, Max Kam-Kwan, et al.
Publicado: (2023)

Establishment of a Hepatocyte Cell Line Producing Growth‐promoting Factors for Liver‐colonizing Tumor Cells
por: Yamori, Takao, et al.
Publicado: (1996)

Tumor Microenvironment in Hepatocellular Carcinoma: Key Players for Immunotherapy
por: Feng, Hai, et al.
Publicado: (2022)

GPER: An Estrogen Receptor Key in Metastasis and Tumoral Microenvironments
por: Tirado-Garibay, Ana Carolina, et al.
Publicado: (2023)

Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment
por: Yang, Li, et al.
Publicado: (2019)

Regulation of Tumor Growth and Metastasis: The Role of Tumor Microenvironment
por: Goubran, Hadi A, et al.
Publicado: (2014)

Combined Stimulation with the Tumor Necrosis Factor α and the Epidermal Growth Factor Promotes the Proliferation of Hepatocytes in Rat Liver Cultured Slices
por: Finot, Francis, et al.
Publicado: (2012)

Transforming Growth Factor-β Signaling Pathway in Colorectal Cancer and Its Tumor Microenvironment
por: Itatani, Yoshiro, et al.
Publicado: (2019)

The Breast Tumor Microenvironment: A Key Player in Metastatic Spread
por: Terceiro, Lucas E. L., et al.
Publicado: (2021)

GARP: A Key Target to Evaluate Tumor Immunosuppressive Microenvironment
por: Bouchard, Alexanne, et al.
Publicado: (2021)

Transforming Growth Factor-β: An Agent of Change in the Tumor Microenvironment
por: Stuelten, Christina H., et al.
Publicado: (2021)

Hepatocyte growth factor-like protein is required for prostate tumor growth in the TRAMP mouse model
por: Vasiliauskas, Juozas, et al.
Publicado: (2014)

Tumor Microenvironment: Lactic Acid Promotes Tumor Development
por: Gao, Yuting, et al.
Publicado: (2022)

Tissue factor in tumor microenvironment: a systematic review
por: Han, Xiao, et al.
Publicado: (2014)

Dendritic cells in tumor microenvironment promoted the neuropathic pain via paracrine inflammatory and growth factors
por: Wang, Zhun, et al.
Publicado: (2020)

Macrophage-derived IL-1β stimulates Wnt signaling and growth of colon cancer cells; a crosstalk interrupted by vitamin D(3)
por: Kaler, Pawan, et al.
Publicado: (2009)

A key driver to promote HCC: Cellular crosstalk in tumor microenvironment
por: Liu, Pengyue, et al.
Publicado: (2023)

Crosstalk between Tumor-Associated Macrophages and MicroRNAs: A Key Role in Tumor Microenvironment
por: Zhou, Xianghong, et al.
Publicado: (2022)

Vascular Endothelial Growth Factor, a Key Modulator of the Anti-Tumor Immune Response
por: Geindreau, Mannon, et al.
Publicado: (2021)

Tumor Microenvironment: Key Players in Triple Negative Breast Cancer Immunomodulation
por: Zheng, Hongmei, et al.
Publicado: (2021)

Stk10 Deficiency in Mice Promotes Tumor Growth by Dysregulating the Tumor Microenvironment
por: Ma, Jin-Xia, et al.
Publicado: (2022)

Mechanisms of Hepatocyte Growth Factor Activation in Cancer Tissues
por: Kawaguchi, Makiko, et al.
Publicado: (2014)

Transforming growth factor-β and breast cancer: Tumor promoting effects of transforming growth factor-β
por: Dumont, Nancy, et al.
Publicado: (2000)

The Role of Tumor Necrosis Factor in Manipulating the Immunological Response of Tumor Microenvironment
por: Laha, Dipranjan, et al.
Publicado: (2021)

Vav1 promotes lung cancer growth by instigating tumor-microenvironment cross-talk via growth factor secretion
por: Sebban, Shulamit, et al.
Publicado: (2014)

The Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy
por: Russell, Bonnie L., et al.
Publicado: (2021)

Hepatocyte growth factor and the hepatocyte growth factor receptor signalling complex as targets in cancer therapies
por: Jiang, W.G.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_d7g5tq4ukeie7o02nh9bidreth