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Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study

BACKGROUND: TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent the molecular markers microsatellite instability (MSI) and mutations in BRAF or KRAS improve prognostic estimation in multivaria...

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Detalles Bibliográficos
Autores principales: Dienstmann, R., Mason, M. J., Sinicrope, F. A., Phipps, A. I., Tejpar, S., Nesbakken, A., Danielsen, S. A., Sveen, A., Buchanan, D. D., Clendenning, M., Rosty, C., Bot, B., Alberts, S. R., Milburn Jessup, J., Lothe, R. A., Delorenzi, M., Newcomb, P. A., Sargent, D., Guinney, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406760/
https://www.ncbi.nlm.nih.gov/pubmed/28453697
http://dx.doi.org/10.1093/annonc/mdx052