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Epstein–Barr virus-associated gastric cancer reveals intratumoral heterogeneity of PIK3CA mutations

BACKGROUND: Recent whole-genome sequencing identified four molecular subtypes of gastric cancer (GC), of which the subgroup of Epstein–Barr virus-associated GC (EBVaGC) showed a significant enrichment of PIK3CA mutations. We here aimed to validate independently the enrichment of PIK3CA mutations in...

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Detalles Bibliográficos
Autores principales:	Böger, C., Krüger, S., Behrens, H. M., Bock, S., Haag, J., Kalthoff, H., Röcken, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406766/ https://www.ncbi.nlm.nih.gov/pubmed/28453696 http://dx.doi.org/10.1093/annonc/mdx047

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