TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK/Tnfsf12) is a cytokine implicated in different steps associated with vascular remodeling. However, the role of TWEAK under hyperglycemic conditions is currently unknown. Using two different approaches, genetic deletion of Tnfsf12 and treatm...

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Detalles Bibliográficos
Autores principales: Fernández-Laso, Valvanera, Sastre, Cristina, Méndez-Barbero, Nerea, Egido, Jesús, Martín-Ventura, Jose L., Gómez-Guerrero, Carmen, Blanco-Colio, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406837/
https://www.ncbi.nlm.nih.gov/pubmed/28447667
http://dx.doi.org/10.1038/srep46679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406837/
https://www.ncbi.nlm.nih.gov/pubmed/28447667
http://dx.doi.org/10.1038/srep46679

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