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MYC, Cell Competition, and Cell Death in Cancer: The Inseparable Triad
Deregulation of MYC family proteins in cancer is associated with a global reprogramming of gene expression, ultimately promoting glycolytic pathways, cell growth, and proliferation. It is well known that MYC upregulation triggers cell-autonomous apoptosis in normal tissues, while frankly malignant c...
Autores principales: | Di Giacomo, Simone, Sollazzo, Manuela, Paglia, Simona, Grifoni, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406867/ https://www.ncbi.nlm.nih.gov/pubmed/28420161 http://dx.doi.org/10.3390/genes8040120 |
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