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Sample size and power determination when limited preliminary information is available

BACKGROUND: We describe a novel strategy for power and sample size determination developed for studies utilizing investigational technologies with limited available preliminary data, specifically of imaging biomarkers. We evaluated diffuse optical spectroscopic imaging (DOSI), an experimental noninv...

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Detalles Bibliográficos
Autores principales:	McLaren, Christine E., Chen, Wen-Pin, O’Sullivan, Thomas D., Gillen, Daniel L., Su, Min-Ying, Chen, Jeon H., Tromberg, Bruce J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406943/ https://www.ncbi.nlm.nih.gov/pubmed/28446127 http://dx.doi.org/10.1186/s12874-017-0329-1

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