Cargando…

Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid

BACKGROUND: Canine leishmaniosis (CanL) has been in the spotlight since the 2009 outbreak of human leishmaniosis in Madrid. In the framework of the Leishmaniosis Surveillance Programme set up in Madrid, this study examines Leishmania-specific seroprevalences in stray dogs for the outbreak area and r...

Descripción completa

Detalles Bibliográficos
Autores principales: Miró, Guadalupe, Müller, Aurora, Montoya, Ana, Checa, Rocía, Marino, Valentina, Marino, Eloy, Fuster, Fernando, Escacena, Cristina, Descalzo, Miguel Angel, Gálvez, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406968/
https://www.ncbi.nlm.nih.gov/pubmed/28446214
http://dx.doi.org/10.1186/s13071-017-2147-z
_version_ 1783232070981517312
author Miró, Guadalupe
Müller, Aurora
Montoya, Ana
Checa, Rocía
Marino, Valentina
Marino, Eloy
Fuster, Fernando
Escacena, Cristina
Descalzo, Miguel Angel
Gálvez, Rosa
author_facet Miró, Guadalupe
Müller, Aurora
Montoya, Ana
Checa, Rocía
Marino, Valentina
Marino, Eloy
Fuster, Fernando
Escacena, Cristina
Descalzo, Miguel Angel
Gálvez, Rosa
author_sort Miró, Guadalupe
collection PubMed
description BACKGROUND: Canine leishmaniosis (CanL) has been in the spotlight since the 2009 outbreak of human leishmaniosis in Madrid. In the framework of the Leishmaniosis Surveillance Programme set up in Madrid, this study examines Leishmania-specific seroprevalences in stray dogs for the outbreak area and rest of the Madrid region over the period spanning from the outbreak to the present (2009–2016). These data are of interest because stray dogs could be sentinels for disease surveillance in endemic areas. Since 2011, we have also been monitoring owned dogs in the outbreak area. METHODS: Over the study period, Leishmania infantum seroprevalence was determined in 2,123 stray dogs from the outbreak and non-outbreak areas. A serological study was also performed for owned dogs in the outbreak area: high-risk dogs such as hunting or farm dogs (n = 1,722) and pets (n = 1372). All dogs were examined and blood was collected. The variables recorded for each animal were: breed, age, sex, and clinical history indicating if the animal was healthy or clinically suspected of having any disease, and if they showed a clinical picture compatible with CanL. RESULTS: Seroprevalences of L. infantum in stray dogs were similar in the two areas examined: 4.7% (20 out of 346) in the outbreak area and 5.4% (96 out of 1,777) in the remaining Madrid region (χ (2) = 0.080, P = 0.777). A significant association was found between seroprevalence and age (z = -6.319; P < 0.001). Seroprevalence in owned dogs in the outbreak area was 2.1% in high-risk dogs (37 out of 1,722) and 1.2% in pets (17 out of 1,372) (χ (2) = 3.561, P = 0.0591). CONCLUSIONS: Both stray and owned dogs do not seem to play an important role in maintaining the transmission cycle of L. infantum in the Madrid outbreak area. The stable seroprevalence of infection observed in sentinel dogs suggests the good clinical management and prevention of CanL by local practitioners in owned dogs.
format Online
Article
Text
id pubmed-5406968
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-54069682017-04-27 Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid Miró, Guadalupe Müller, Aurora Montoya, Ana Checa, Rocía Marino, Valentina Marino, Eloy Fuster, Fernando Escacena, Cristina Descalzo, Miguel Angel Gálvez, Rosa Parasit Vectors Short Report BACKGROUND: Canine leishmaniosis (CanL) has been in the spotlight since the 2009 outbreak of human leishmaniosis in Madrid. In the framework of the Leishmaniosis Surveillance Programme set up in Madrid, this study examines Leishmania-specific seroprevalences in stray dogs for the outbreak area and rest of the Madrid region over the period spanning from the outbreak to the present (2009–2016). These data are of interest because stray dogs could be sentinels for disease surveillance in endemic areas. Since 2011, we have also been monitoring owned dogs in the outbreak area. METHODS: Over the study period, Leishmania infantum seroprevalence was determined in 2,123 stray dogs from the outbreak and non-outbreak areas. A serological study was also performed for owned dogs in the outbreak area: high-risk dogs such as hunting or farm dogs (n = 1,722) and pets (n = 1372). All dogs were examined and blood was collected. The variables recorded for each animal were: breed, age, sex, and clinical history indicating if the animal was healthy or clinically suspected of having any disease, and if they showed a clinical picture compatible with CanL. RESULTS: Seroprevalences of L. infantum in stray dogs were similar in the two areas examined: 4.7% (20 out of 346) in the outbreak area and 5.4% (96 out of 1,777) in the remaining Madrid region (χ (2) = 0.080, P = 0.777). A significant association was found between seroprevalence and age (z = -6.319; P < 0.001). Seroprevalence in owned dogs in the outbreak area was 2.1% in high-risk dogs (37 out of 1,722) and 1.2% in pets (17 out of 1,372) (χ (2) = 3.561, P = 0.0591). CONCLUSIONS: Both stray and owned dogs do not seem to play an important role in maintaining the transmission cycle of L. infantum in the Madrid outbreak area. The stable seroprevalence of infection observed in sentinel dogs suggests the good clinical management and prevention of CanL by local practitioners in owned dogs. BioMed Central 2017-04-26 /pmc/articles/PMC5406968/ /pubmed/28446214 http://dx.doi.org/10.1186/s13071-017-2147-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Miró, Guadalupe
Müller, Aurora
Montoya, Ana
Checa, Rocía
Marino, Valentina
Marino, Eloy
Fuster, Fernando
Escacena, Cristina
Descalzo, Miguel Angel
Gálvez, Rosa
Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid
title Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid
title_full Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid
title_fullStr Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid
title_full_unstemmed Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid
title_short Epidemiological role of dogs since the human leishmaniosis outbreak in Madrid
title_sort epidemiological role of dogs since the human leishmaniosis outbreak in madrid
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406968/
https://www.ncbi.nlm.nih.gov/pubmed/28446214
http://dx.doi.org/10.1186/s13071-017-2147-z
work_keys_str_mv AT miroguadalupe epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT mulleraurora epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT montoyaana epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT checarocia epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT marinovalentina epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT marinoeloy epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT fusterfernando epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT escacenacristina epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT descalzomiguelangel epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid
AT galvezrosa epidemiologicalroleofdogssincethehumanleishmaniosisoutbreakinmadrid