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GlyCAM1 negatively regulates monocyte entry into the optic nerve head and contributes to radiation-based protection in glaucoma
BACKGROUND: We previously reported a profound long-term neuroprotection subsequent to a single radiation-therapy in the DBA/2J mouse model of glaucoma. This neuroprotection prevents entry of monocyte-like immune cells into the optic nerve head during glaucoma. Gene expression studies in radiation-tr...
Autores principales: | Williams, Pete A., Braine, Catherine E., Foxworth, Nicole E., Cochran, Kelly E., John, Simon W. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406973/ https://www.ncbi.nlm.nih.gov/pubmed/28446179 http://dx.doi.org/10.1186/s12974-017-0868-8 |
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