Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality

We report a 66% reduction in neonatal tetanus mortality after introducing a new management bundle integrating antibiotic therapy, muscle relaxation and invasive monitoring. The latter allowed rapid detection of autonomic instability which was treated with magnesium sulphate. This is the first report...

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Detalles Bibliográficos
Autores principales: Trieu, Huynh T., Lubis, Inke N., Qui, Phan T., Yen, Lam M., Wills, Bridget, Thwaites, C. Louise, Sabanathan, Saraswathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407131/
https://www.ncbi.nlm.nih.gov/pubmed/26407289
http://dx.doi.org/10.1093/jpids/piv059
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author Trieu, Huynh T.
Lubis, Inke N.
Qui, Phan T.
Yen, Lam M.
Wills, Bridget
Thwaites, C. Louise
Sabanathan, Saraswathy
author_facet Trieu, Huynh T.
Lubis, Inke N.
Qui, Phan T.
Yen, Lam M.
Wills, Bridget
Thwaites, C. Louise
Sabanathan, Saraswathy
author_sort Trieu, Huynh T.
collection PubMed
description We report a 66% reduction in neonatal tetanus mortality after introducing a new management bundle integrating antibiotic therapy, muscle relaxation and invasive monitoring. The latter allowed rapid detection of autonomic instability which was treated with magnesium sulphate. This is the first report of its use in neonatal tetanus.
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spelling pubmed-54071312017-05-03 Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality Trieu, Huynh T. Lubis, Inke N. Qui, Phan T. Yen, Lam M. Wills, Bridget Thwaites, C. Louise Sabanathan, Saraswathy J Pediatric Infect Dis Soc Brief Reports We report a 66% reduction in neonatal tetanus mortality after introducing a new management bundle integrating antibiotic therapy, muscle relaxation and invasive monitoring. The latter allowed rapid detection of autonomic instability which was treated with magnesium sulphate. This is the first report of its use in neonatal tetanus. Oxford University Press 2016-06 2015-09-09 /pmc/articles/PMC5407131/ /pubmed/26407289 http://dx.doi.org/10.1093/jpids/piv059 Text en © The Author 2015. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Trieu, Huynh T.
Lubis, Inke N.
Qui, Phan T.
Yen, Lam M.
Wills, Bridget
Thwaites, C. Louise
Sabanathan, Saraswathy
Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality
title Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality
title_full Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality
title_fullStr Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality
title_full_unstemmed Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality
title_short Neonatal Tetanus in Vietnam: Comprehensive Intensive Care Support Improves Mortality
title_sort neonatal tetanus in vietnam: comprehensive intensive care support improves mortality
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407131/
https://www.ncbi.nlm.nih.gov/pubmed/26407289
http://dx.doi.org/10.1093/jpids/piv059
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