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Fecal Microbiota Transfer for Multidrug-Resistant Gram-Negatives: A Clinical Success Combined With Microbiological Failure

Combined fecal microbiota transfer and antibiotic treatment prevented recurrences of urinary tract infections with multidrug-resistant (MDR) Pseudomonas aeruginosa, but it failed to eradicate intestinal colonization with MDR Escherichia coli. Based on microbiota analysis, failure was not associated...

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Detalles Bibliográficos
Autores principales: Stalenhoef, Janneke E., Terveer, Elisabeth M., Knetsch, Cornelis W., van‘t Hof, Peter J., Vlasveld, Imro N., Keller, Josbert J., Visser, Leo G., Kuijper, Eduard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407212/
https://www.ncbi.nlm.nih.gov/pubmed/28470023
http://dx.doi.org/10.1093/ofid/ofx047
Descripción
Sumario:Combined fecal microbiota transfer and antibiotic treatment prevented recurrences of urinary tract infections with multidrug-resistant (MDR) Pseudomonas aeruginosa, but it failed to eradicate intestinal colonization with MDR Escherichia coli. Based on microbiota analysis, failure was not associated with distinct diminished microbiota diversity.