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Celiac disease in Iran: a systematic review and meta-analysis

INTRODUCTION: Celiac disease (CD) is a chronic autoimmune-mediated disorder with both intestinal and systemic manifestations. The aim of this study was to determine the prevalence of celiac disease in Iran. METHODS: We conducted a systematic search on Embase, Pub Med, Web of Science, Google Scholar,...

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Autores principales: Mohammadibakhsh, Roghayeh, Sohrabi, Rahim, Salemi, Morteza, Mirghaed, Masood Taheri, Behzadifar, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Electronic physician 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407219/
https://www.ncbi.nlm.nih.gov/pubmed/28461861
http://dx.doi.org/10.19082/3883
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author Mohammadibakhsh, Roghayeh
Sohrabi, Rahim
Salemi, Morteza
Mirghaed, Masood Taheri
Behzadifar, Masoud
author_facet Mohammadibakhsh, Roghayeh
Sohrabi, Rahim
Salemi, Morteza
Mirghaed, Masood Taheri
Behzadifar, Masoud
author_sort Mohammadibakhsh, Roghayeh
collection PubMed
description INTRODUCTION: Celiac disease (CD) is a chronic autoimmune-mediated disorder with both intestinal and systemic manifestations. The aim of this study was to determine the prevalence of celiac disease in Iran. METHODS: We conducted a systematic search on Embase, Pub Med, Web of Science, Google Scholar, MagIran, Scientific Information database (SID) and Iranmedex from 2003 through to November 2015. The Der-Simonian/Laird’s (DL), with a 95% confidence interval employed to estimate the overall pooled prevalence. Heterogeneity was investigated by using subgroup analysis based on sample size and time of study. RESULTS: Sixty-three studies with 36,833 participants met inclusion criteria for analysis. The overall prevalence of celiac disease in 63 studies that had used serological tests for the diagnosis was observed as 3% (95% CI: 0.03–0.03) and the overall prevalence of celiac disease in studies that had used biopsy method for diagnosis was observed as 2% (95% CI: 0.01–0.02). CONCLUSION: The prevalence of celiac disease in Iran was similar or even higher than world-wide reported.
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spelling pubmed-54072192017-05-01 Celiac disease in Iran: a systematic review and meta-analysis Mohammadibakhsh, Roghayeh Sohrabi, Rahim Salemi, Morteza Mirghaed, Masood Taheri Behzadifar, Masoud Electron Physician Meta-Analysis INTRODUCTION: Celiac disease (CD) is a chronic autoimmune-mediated disorder with both intestinal and systemic manifestations. The aim of this study was to determine the prevalence of celiac disease in Iran. METHODS: We conducted a systematic search on Embase, Pub Med, Web of Science, Google Scholar, MagIran, Scientific Information database (SID) and Iranmedex from 2003 through to November 2015. The Der-Simonian/Laird’s (DL), with a 95% confidence interval employed to estimate the overall pooled prevalence. Heterogeneity was investigated by using subgroup analysis based on sample size and time of study. RESULTS: Sixty-three studies with 36,833 participants met inclusion criteria for analysis. The overall prevalence of celiac disease in 63 studies that had used serological tests for the diagnosis was observed as 3% (95% CI: 0.03–0.03) and the overall prevalence of celiac disease in studies that had used biopsy method for diagnosis was observed as 2% (95% CI: 0.01–0.02). CONCLUSION: The prevalence of celiac disease in Iran was similar or even higher than world-wide reported. Electronic physician 2017-03-25 /pmc/articles/PMC5407219/ /pubmed/28461861 http://dx.doi.org/10.19082/3883 Text en © 2017 The Authors This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/3.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Meta-Analysis
Mohammadibakhsh, Roghayeh
Sohrabi, Rahim
Salemi, Morteza
Mirghaed, Masood Taheri
Behzadifar, Masoud
Celiac disease in Iran: a systematic review and meta-analysis
title Celiac disease in Iran: a systematic review and meta-analysis
title_full Celiac disease in Iran: a systematic review and meta-analysis
title_fullStr Celiac disease in Iran: a systematic review and meta-analysis
title_full_unstemmed Celiac disease in Iran: a systematic review and meta-analysis
title_short Celiac disease in Iran: a systematic review and meta-analysis
title_sort celiac disease in iran: a systematic review and meta-analysis
topic Meta-Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407219/
https://www.ncbi.nlm.nih.gov/pubmed/28461861
http://dx.doi.org/10.19082/3883
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