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A minimal model of burst-noise induced bistability
We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified version of the Schlögl model, which is a chemical reaction syst...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407650/ https://www.ncbi.nlm.nih.gov/pubmed/28448638 http://dx.doi.org/10.1371/journal.pone.0176410 |
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author | Falk, Johannes Mendler, Marc Drossel, Barbara |
author_facet | Falk, Johannes Mendler, Marc Drossel, Barbara |
author_sort | Falk, Johannes |
collection | PubMed |
description | We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified version of the Schlögl model, which is a chemical reaction system with only one type of molecule. The strength of the intrinsic noise is varied without changing the deterministic description by introducing bursts in the autocatalytic production step. We study the transitions between monostable and bistable behavior in this system by evaluating the number of maxima of the stationary probability distribution. We find that changing the size of bursts can destroy and even induce saddle-node bifurcations. This means that a bursty production of molecules can qualitatively change the dynamics of a chemical reaction system even when the deterministic description remains unchanged. |
format | Online Article Text |
id | pubmed-5407650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-54076502017-05-14 A minimal model of burst-noise induced bistability Falk, Johannes Mendler, Marc Drossel, Barbara PLoS One Research Article We investigate the influence of intrinsic noise on stable states of a one-dimensional dynamical system that shows in its deterministic version a saddle-node bifurcation between monostable and bistable behaviour. The system is a modified version of the Schlögl model, which is a chemical reaction system with only one type of molecule. The strength of the intrinsic noise is varied without changing the deterministic description by introducing bursts in the autocatalytic production step. We study the transitions between monostable and bistable behavior in this system by evaluating the number of maxima of the stationary probability distribution. We find that changing the size of bursts can destroy and even induce saddle-node bifurcations. This means that a bursty production of molecules can qualitatively change the dynamics of a chemical reaction system even when the deterministic description remains unchanged. Public Library of Science 2017-04-27 /pmc/articles/PMC5407650/ /pubmed/28448638 http://dx.doi.org/10.1371/journal.pone.0176410 Text en © 2017 Falk et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Falk, Johannes Mendler, Marc Drossel, Barbara A minimal model of burst-noise induced bistability |
title | A minimal model of burst-noise induced bistability |
title_full | A minimal model of burst-noise induced bistability |
title_fullStr | A minimal model of burst-noise induced bistability |
title_full_unstemmed | A minimal model of burst-noise induced bistability |
title_short | A minimal model of burst-noise induced bistability |
title_sort | minimal model of burst-noise induced bistability |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407650/ https://www.ncbi.nlm.nih.gov/pubmed/28448638 http://dx.doi.org/10.1371/journal.pone.0176410 |
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