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Integrin β1 activation induces an anti-melanoma host response
TGF-β is a cytokine thought to function as a tumor promoter in advanced malignancies. In this setting, TGF-β increases cancer cell proliferation, survival, and migration, and orchestrates complex, pro-tumorigenic changes in the tumor microenvironment. Here, we find that in melanoma, integrin β1-medi...
Autores principales: | Ritsma, Laila, Dey-Guha, Ipsita, Talele, Nilesh, Sole, Xavier, Salony, Chowdhury, Joeeta, Ross, Kenneth N., Ramaswamy, Sridhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407755/ https://www.ncbi.nlm.nih.gov/pubmed/28448494 http://dx.doi.org/10.1371/journal.pone.0175300 |
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