A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database

The liver and the kidney are the most common targets of chemical toxicity, due to their major metabolic and excretory functions. However, since the liver is directly involved in biotransformation, compounds in many currently and normally used drugs could affect it adversely. Most chemical compounds...

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Detalles Bibliográficos
Autores principales: Rueda-Zárate, Héctor A., Imaz-Rosshandler, Iván, Cárdenas-Ovando, Roberto A., Castillo-Fernández, Juan E., Noguez-Monroy, Julieta, Rangel-Escareño, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407788/
https://www.ncbi.nlm.nih.gov/pubmed/28448553
http://dx.doi.org/10.1371/journal.pone.0176284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407788/
https://www.ncbi.nlm.nih.gov/pubmed/28448553
http://dx.doi.org/10.1371/journal.pone.0176284

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