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A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database
The liver and the kidney are the most common targets of chemical toxicity, due to their major metabolic and excretory functions. However, since the liver is directly involved in biotransformation, compounds in many currently and normally used drugs could affect it adversely. Most chemical compounds...
Autores principales: | Rueda-Zárate, Héctor A., Imaz-Rosshandler, Iván, Cárdenas-Ovando, Roberto A., Castillo-Fernández, Juan E., Noguez-Monroy, Julieta, Rangel-Escareño, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407788/ https://www.ncbi.nlm.nih.gov/pubmed/28448553 http://dx.doi.org/10.1371/journal.pone.0176284 |
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