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Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study
PURPOSE: To investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing. METHODS: This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the fo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407804/ https://www.ncbi.nlm.nih.gov/pubmed/28448513 http://dx.doi.org/10.1371/journal.pone.0175921 |
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author | Guo, Yin Liu, Li Juan Tang, Ping Lv, Yan Yun Feng, Yi Xu, Liang Jonas, Jost B. |
author_facet | Guo, Yin Liu, Li Juan Tang, Ping Lv, Yan Yun Feng, Yi Xu, Liang Jonas, Jost B. |
author_sort | Guo, Yin |
collection | PubMed |
description | PURPOSE: To investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing. METHODS: This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the follow-up examination in 2015. At baseline and in yearly follow-up examinations, the children underwent a comprehensive eye examination including auto-refractometry, ocular biometry with measurement of axial length, and fundus photography. The parents underwent a standardized interview. RESULTS: During the study period, the mean axial length elongated by 1.15±0.56mm in boys and 1.10±0.63mm in girls. At baseline and at the end of follow-up, axial length was significantly (P<0.001) longer in boys, with no difference (P = 0.50) between genders in axial elongation. In multivariate analysis, greater axial elongation was associated (regression coefficient r(2):0.15) with less time spent outdoors (P = 0.004; standardized coefficient beta: -0.22), more time spent indoors with studying (P = 0.02; beta: 0.18) and paternal myopia (P = 0.03; beta: 0.16). Larger increases in the axial length/anterior corneal curvature (AL/CC) ratio were associated (r(2):0.09) with less time spent outdoors (PP = 0.003; beta: -0.22) and maternal myopia (PP = 0.02; beta: 0.18). CONCLUSIONS: Myopic axial elongation during a 4-year follow-up was associated with shorter time spent outdoors and longer time spent indoors studying and with parental myopia. Other factors such as level of paternal education, family income, gender and region of habitation were significantly associated with axial elongation and with myopia progression only in univariate analysis. |
format | Online Article Text |
id | pubmed-5407804 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-54078042017-05-14 Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study Guo, Yin Liu, Li Juan Tang, Ping Lv, Yan Yun Feng, Yi Xu, Liang Jonas, Jost B. PLoS One Research Article PURPOSE: To investigate factors associated with ocular axial elongation and myopia progression during a 4-year follow-up in primary school children in Beijing. METHODS: This school-based study included 382 grade-1 children at baseline in 2011 (age:6.3±0.4 years) with 305 (79.8%) returning for the follow-up examination in 2015. At baseline and in yearly follow-up examinations, the children underwent a comprehensive eye examination including auto-refractometry, ocular biometry with measurement of axial length, and fundus photography. The parents underwent a standardized interview. RESULTS: During the study period, the mean axial length elongated by 1.15±0.56mm in boys and 1.10±0.63mm in girls. At baseline and at the end of follow-up, axial length was significantly (P<0.001) longer in boys, with no difference (P = 0.50) between genders in axial elongation. In multivariate analysis, greater axial elongation was associated (regression coefficient r(2):0.15) with less time spent outdoors (P = 0.004; standardized coefficient beta: -0.22), more time spent indoors with studying (P = 0.02; beta: 0.18) and paternal myopia (P = 0.03; beta: 0.16). Larger increases in the axial length/anterior corneal curvature (AL/CC) ratio were associated (r(2):0.09) with less time spent outdoors (PP = 0.003; beta: -0.22) and maternal myopia (PP = 0.02; beta: 0.18). CONCLUSIONS: Myopic axial elongation during a 4-year follow-up was associated with shorter time spent outdoors and longer time spent indoors studying and with parental myopia. Other factors such as level of paternal education, family income, gender and region of habitation were significantly associated with axial elongation and with myopia progression only in univariate analysis. Public Library of Science 2017-04-27 /pmc/articles/PMC5407804/ /pubmed/28448513 http://dx.doi.org/10.1371/journal.pone.0175921 Text en © 2017 Guo et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Guo, Yin Liu, Li Juan Tang, Ping Lv, Yan Yun Feng, Yi Xu, Liang Jonas, Jost B. Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study |
title | Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study |
title_full | Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study |
title_fullStr | Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study |
title_full_unstemmed | Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study |
title_short | Outdoor activity and myopia progression in 4-year follow-up of Chinese primary school children: The Beijing Children Eye Study |
title_sort | outdoor activity and myopia progression in 4-year follow-up of chinese primary school children: the beijing children eye study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407804/ https://www.ncbi.nlm.nih.gov/pubmed/28448513 http://dx.doi.org/10.1371/journal.pone.0175921 |
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