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Brorin is required for neurogenesis, gliogenesis, and commissural axon guidance in the zebrafish forebrain
Bmps regulate numerous neural functions with their regulators. We previously identified Brorin, a neural-specific secreted antagonist of Bmp signaling, in humans, mice, and zebrafish. Mouse Brorin has two cysteine-rich domains containing 10 cysteine residues in its core region, and these are located...
Autores principales: | Miyake, Ayumi, Mekata, Yoko, Fujibayashi, Hidenori, Nakanishi, Kazuya, Konishi, Morichika, Itoh, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407822/ https://www.ncbi.nlm.nih.gov/pubmed/28448525 http://dx.doi.org/10.1371/journal.pone.0176036 |
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