Inferring modulators of genetic interactions with epistatic nested effects models

Maps of genetic interactions can dissect functional redundancies in cellular networks. Gene expression profiles as high-dimensional molecular readouts of combinatorial perturbations provide a detailed view of genetic interactions, but can be hard to interpret if different gene sets respond in differ...

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Detalles Bibliográficos
Autores principales: Pirkl, Martin, Diekmann, Madeline, van der Wees, Marlies, Beerenwinkel, Niko, Fröhlich, Holger, Markowetz, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407847/
https://www.ncbi.nlm.nih.gov/pubmed/28406896
http://dx.doi.org/10.1371/journal.pcbi.1005496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407847/
https://www.ncbi.nlm.nih.gov/pubmed/28406896
http://dx.doi.org/10.1371/journal.pcbi.1005496

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