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Inferring modulators of genetic interactions with epistatic nested effects models
Maps of genetic interactions can dissect functional redundancies in cellular networks. Gene expression profiles as high-dimensional molecular readouts of combinatorial perturbations provide a detailed view of genetic interactions, but can be hard to interpret if different gene sets respond in differ...
Autores principales: | Pirkl, Martin, Diekmann, Madeline, van der Wees, Marlies, Beerenwinkel, Niko, Fröhlich, Holger, Markowetz, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407847/ https://www.ncbi.nlm.nih.gov/pubmed/28406896 http://dx.doi.org/10.1371/journal.pcbi.1005496 |
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