GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome

Upon viral infection, retinoic acid–inducible gene I–like receptors (RLRs) recognize viral RNA and trigger a series of signaling events, leading to the induction of type I interferons (IFNs). These processes are delicately regulated to prevent excessive and harmful immune responses. In this study, w...

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Detalles Bibliográficos
Autores principales: Nie, Ying, Ran, Yong, Zhang, Hong-Yan, Huang, Zhe-Fu, Pan, Zhao-Yi, Wang, Su-Yun, Wang, Yan-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407853/
https://www.ncbi.nlm.nih.gov/pubmed/28414768
http://dx.doi.org/10.1371/journal.ppat.1006328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407853/
https://www.ncbi.nlm.nih.gov/pubmed/28414768
http://dx.doi.org/10.1371/journal.ppat.1006328

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