Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells

Mechanotransducer channels at the tips of sensory stereocilia of inner ear hair cells are gated by the tension of 'tip links' interconnecting stereocilia. To ensure maximal sensitivity, tip links are tensioned at rest, resulting in a continuous influx of Ca(2+) into the cell. Here, we show...

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Detalles Bibliográficos
Autores principales: Vélez-Ortega, A Catalina, Freeman, Mary J, Indzhykulian, Artur A, Grossheim, Jonathan M, Frolenkov, Gregory I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407859/
https://www.ncbi.nlm.nih.gov/pubmed/28350294
http://dx.doi.org/10.7554/eLife.24661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407859/
https://www.ncbi.nlm.nih.gov/pubmed/28350294
http://dx.doi.org/10.7554/eLife.24661

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