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Crystal structure of the essential biotin‐dependent carboxylase AccA3 from Mycobacterium tuberculosis

Biotin‐dependent acetyl‐CoA carboxylases catalyze the committed step in type II fatty acid biosynthesis, the main route for production of membrane phospholipids in bacteria, and are considered a key target for antibacterial drug discovery. Here we describe the first structure of AccA3, an essential...

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Detalles Bibliográficos
Autores principales:	Bennett, Matthew, Högbom, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407890/ https://www.ncbi.nlm.nih.gov/pubmed/28469974 http://dx.doi.org/10.1002/2211-5463.12212

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