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Estrogen inhibits starvation‐induced apoptosis in osteocytes by a redox‐independent process involving association of JNK and glutathione S‐transferase P1‐1
Estrogen deficiency causes bone loss as a result of microdamage, oxidative stress, and osteocyte apoptosis. A relationship between oxidative stress‐induced apoptosis, c‐Jun N‐terminal kinase (JNK) activation, and expression of factors involved in bone remodeling has been demonstrated in osteocytes....
Autores principales: | Domazetovic, Vladana, Fontani, Filippo, Marcucci, Gemma, Iantomasi, Teresa, Brandi, Maria Luisa, Vincenzini, Maria Teresa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407897/ https://www.ncbi.nlm.nih.gov/pubmed/28469982 http://dx.doi.org/10.1002/2211-5463.12216 |
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