Heterogeneity of Phenotype and Function Reflects the Multistage Development of T Follicular Helper Cells

T follicular helper cells (Tfh) provide crucial signals for germinal center (GC) formation, but Tfh populations are heterogeneous. While PD1(hi) Tfh are important in the GC response, the function of the PD1(lo) Tfh-like subset is unknown. We show that these cells, like the PD1(hi) GC–Tfh, depend upo...

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Detalles Bibliográficos
Autores principales: Trüb, Marta, Barr, Tom A., Morrison, Vicky L., Brown, Sheila, Caserta, Stefano, Rixon, Jordan, Ivens, Alasdair, Gray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408024/
https://www.ncbi.nlm.nih.gov/pubmed/28503175
http://dx.doi.org/10.3389/fimmu.2017.00489

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