A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646

Streptomyces cinnamoneus DSM 40646 produces the Class II lantibiotic cinnamycin which possesses an unusual mechanism of action, binding to the membrane lipid phosphatidylethanolamine (PE) to elicit its antimicrobial activity. A comprehensive analysis of the cinnamycin biosynthetic gene cluster has u...

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Detalles Bibliográficos
Autores principales: O’Rourke, Sean, Widdick, David, Bibb, Mervyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Genetics and Molecular Biology of Industrial Organisms - Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408092/
https://www.ncbi.nlm.nih.gov/pubmed/27858169
http://dx.doi.org/10.1007/s10295-016-1869-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408092/
https://www.ncbi.nlm.nih.gov/pubmed/27858169
http://dx.doi.org/10.1007/s10295-016-1869-9

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