Helicobacter pylori Strains and Gastric MALT Lymphoma

This article summarizes the main findings concerning Helicobacter pylori associated with gastric MALT lymphoma (GML). Considered together, GML strains based on their virulence factor profile appear to be less virulent than those associated with peptic ulcers or gastric adenocarcinoma. A particular L...

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Detalles Bibliográficos
Autores principales: Floch, Pauline, Mégraud, Francis, Lehours, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408206/
https://www.ncbi.nlm.nih.gov/pubmed/28397767
http://dx.doi.org/10.3390/toxins9040132
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author Floch, Pauline
Mégraud, Francis
Lehours, Philippe
author_facet Floch, Pauline
Mégraud, Francis
Lehours, Philippe
author_sort Floch, Pauline
collection PubMed
description This article summarizes the main findings concerning Helicobacter pylori associated with gastric MALT lymphoma (GML). Considered together, GML strains based on their virulence factor profile appear to be less virulent than those associated with peptic ulcers or gastric adenocarcinoma. A particular Lewis antigen profile has been identified in GML strains and could represent an alternative adaptive mechanism to escape the host immune response thereby allowing continuous antigenic stimulation of infiltrating lymphocytes.
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spelling pubmed-54082062017-05-03 Helicobacter pylori Strains and Gastric MALT Lymphoma Floch, Pauline Mégraud, Francis Lehours, Philippe Toxins (Basel) Review This article summarizes the main findings concerning Helicobacter pylori associated with gastric MALT lymphoma (GML). Considered together, GML strains based on their virulence factor profile appear to be less virulent than those associated with peptic ulcers or gastric adenocarcinoma. A particular Lewis antigen profile has been identified in GML strains and could represent an alternative adaptive mechanism to escape the host immune response thereby allowing continuous antigenic stimulation of infiltrating lymphocytes. MDPI 2017-04-08 /pmc/articles/PMC5408206/ /pubmed/28397767 http://dx.doi.org/10.3390/toxins9040132 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Floch, Pauline
Mégraud, Francis
Lehours, Philippe
Helicobacter pylori Strains and Gastric MALT Lymphoma
title Helicobacter pylori Strains and Gastric MALT Lymphoma
title_full Helicobacter pylori Strains and Gastric MALT Lymphoma
title_fullStr Helicobacter pylori Strains and Gastric MALT Lymphoma
title_full_unstemmed Helicobacter pylori Strains and Gastric MALT Lymphoma
title_short Helicobacter pylori Strains and Gastric MALT Lymphoma
title_sort helicobacter pylori strains and gastric malt lymphoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408206/
https://www.ncbi.nlm.nih.gov/pubmed/28397767
http://dx.doi.org/10.3390/toxins9040132
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