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A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use

BACKGROUND: It has become increasingly apparent that the trophectoderm (TE) at blastocyst stage is much more mosaic than has been appreciated. Whether preimplantation genetic screening (PGS), utilizing a single TE biopsy (TEB), can reliably determine embryo ploidy has, therefore, increasingly been q...

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Detalles Bibliográficos
Autores principales:	Gleicher, Norbert, Metzger, Jacob, Croft, Gist, Kushnir, Vitaly A., Albertini, David F., Barad, David H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408377/ https://www.ncbi.nlm.nih.gov/pubmed/28449669 http://dx.doi.org/10.1186/s12958-017-0251-8

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