YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2

BACKGROUND: Ginkgo biloba has been reported to possess free radical-scavenging antioxidant activity and anti-inflammatory properties. In our pilot study, YY-1224, a terpene trilactone-strengthened extract of G. biloba, showed anti-inflammatory, neurotrophic, and antioxidant effects. RESULTS: We inve...

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Detalles Bibliográficos
Autores principales: Li, Zheng-Yi, Chung, Yoon Hee, Shin, Eun-Joo, Dang, Duy-Khanh, Jeong, Ji Hoon, Ko, Sung Kwon, Nah, Seung-Yeol, Baik, Tae Gon, Jhoo, Jin Hyeong, Ong, Wei-Yi, Nabeshima, Toshitaka, Kim, Hyoung-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408406/
https://www.ncbi.nlm.nih.gov/pubmed/28449688
http://dx.doi.org/10.1186/s12974-017-0866-x

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