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Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions

The epicardium contributes both multi-lineage descendants and paracrine factors to the heart during cardiogenesis and cardiac repair, underscoring its potential for cardiac regenerative medicine. Yet little is known about the cellular and molecular mechanisms that regulate human epicardial developme...

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Detalles Bibliográficos
Autores principales: Bao, Xiaoping, Lian, Xiaojun, Hacker, Timothy A., Schmuck, Eric G., Qian, Tongcheng, Bhute, Vijesh J., Han, Tianxiao, Shi, Mengxuan, Drowley, Lauren, Plowright, Alleyn, Wang, Qing-Dong, Goumans, Marie-Jose, Palecek, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408455/
https://www.ncbi.nlm.nih.gov/pubmed/28462012
http://dx.doi.org/10.1038/s41551-016-0003