FoxO3 increases miR-34a to cause palmitate-induced cholangiocyte lipoapoptosis

Nonalcoholic steatohepatitis (NASH) patients have elevated plasma saturated free fatty acid levels. These toxic fatty acids can induce liver cell death and our recent results demonstrated that the biliary epithelium may be susceptible to lipotoxicity. Here, we explored the molecular mechanisms of ch...

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Detalles Bibliográficos
Autores principales: Natarajan, Sathish Kumar, Stringham, Bailey A., Mohr, Ashley M., Wehrkamp, Cody J., Lu, Sizhao, Phillippi, Mary Anne, Harrison-Findik, Dee, Mott, Justin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408604/
https://www.ncbi.nlm.nih.gov/pubmed/28250026
http://dx.doi.org/10.1194/jlr.M071357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408604/
https://www.ncbi.nlm.nih.gov/pubmed/28250026
http://dx.doi.org/10.1194/jlr.M071357

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