Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages

Oncostatin M (OSM) is a secreted cytokine mainly involved in chronic inflammatory and cardiovascular diseases through binding to OSM receptor β (OSMR-β). Recent studies demonstrated that the presence of OSM contributed to the destabilization of atherosclerotic plaque. To investigate whether OSMR-β d...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Li, Jing, Qin, Juan-Juan, Cheng, Wen-Lin, Zhu, Xueyong, Gong, Fu-Han, She, Zhigang, Huang, Zan, Xia, Hao, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408608/
https://www.ncbi.nlm.nih.gov/pubmed/28258089
http://dx.doi.org/10.1194/jlr.M074112

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