Cargando…
Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6
Hepatitis B X protein (HBx) plays an essential role in the hepatitis B virus (HBV) replication cycle, but the function of HBx has been elusive until recently. It was recently shown that transcription from the HBV genome (covalently-closed circular DNA, cccDNA) is inhibited by the structural maintena...
Autores principales: | Livingston, Christine M., Ramakrishnan, Dhivya, Strubin, Michel, Fletcher, Simon P., Beran, Rudolf K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408675/ https://www.ncbi.nlm.nih.gov/pubmed/28368357 http://dx.doi.org/10.3390/v9040069 |
Ejemplares similares
-
The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection
por: Niu, Congrong, et al.
Publicado: (2017) -
Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes
por: Kornyeyev, Dmytro, et al.
Publicado: (2019) -
Hepatitis B Virus X Protein Function Requires Zinc Binding
por: Ramakrishnan, Dhivya, et al.
Publicado: (2019) -
Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo
por: Allweiss, Lena, et al.
Publicado: (2022) -
The Smc5–Smc6 Complex Is Required to Remove Chromosome Junctions in Meiosis
por: Farmer, Sarah, et al.
Publicado: (2011)