A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Efficacy of candidate antibacterial treatments must be demonstrated in animal models of infection as part of the discovery and development process, preferably in models which mimic the intended clinical indication. A method for inducing robust lung infections in immunocompetent rats and mice is desc...

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Detalles Bibliográficos
Autores principales: Hoover, Jennifer L., Lewandowski, Thomas F., Mininger, Cindy L., Singley, Christine M., Sucoloski, Scott, Rittenhouse, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408714/
https://www.ncbi.nlm.nih.gov/pubmed/28117818
http://dx.doi.org/10.3791/55068

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