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Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction

MOTIVATION: Loops are often vital for protein function, however, their irregular structures make them difficult to model accurately. Current loop modelling algorithms can mostly be divided into two categories: knowledge-based, where databases of fragments are searched to find suitable conformations...

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Detalles Bibliográficos
Autores principales: Marks, Claire, Nowak, Jaroslaw, Klostermann, Stefan, Georges, Guy, Dunbar, James, Shi, Jiye, Kelm, Sebastian, Deane, Charlotte M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408792/
https://www.ncbi.nlm.nih.gov/pubmed/28453681
http://dx.doi.org/10.1093/bioinformatics/btw823